Det medisinske fakultet

Medisinsk avdeling B

Produksjonsdato : 2001-01-23
Katalogtype: Fullformat.

1
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Alagib, K.E.E
Medforf: Børretzen, M
Medforf: Jonsson, R
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Thoen, J
Medforf: Thompson, K.M
Medforf: Natvig, J.B
Tittel:  Structural comparison of rheumatoid factors from patients with primary
          Sjøgren's syndrome, rheumatoid arthritis and healthy immunized donors
Tidskr:  Arthritis and Rheumatism. 41 (9 (suppl))
År:      1998-11
Side(r): S84-S84
Konfer:  American College of Rheumatology 62nd. National Meeting
Sted:    San Diego, USA
Språk:   eng
PublID:  r98029075
StatKat: f
LokalK:  a1

2
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Alagib, K.E.F.
Medforf: Børretzen, M
Medforf: Jonsson, R
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Thoen, J
Medforf: Thompson, K.M
Medforf: Natvig, J.B
Tittel:  Rheumatoid factor (RF) in primary Sjøgren's syndrome (SS)
Tidskr:  Scandinavian Journal of Immunology. 47 (6)
År:      1998
Konfer:  Scandinavian Society Immunology 29th. Meeting
Sted:    Copenhagen, Denmark
Språk:   eng
PublID:  r98029041
StatKat: f
LokalK:  a1

3
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Alarcon-Riquelme, M.
Medforf: Steinsson, K
Medforf: Alarcon-Segovia, D
Medforf: Sturfelt, G
Medforf: Lundberg, I
Medforf: Truedsson, L
Medforf: Alcocer-Varela, J
Medforf: Gordon, C
Medforf: Klareskog, L
Medforf: Kalden, JR
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Tittel:  Cooperative network on the genetics of Systemic Lupus Erythematosus (S
         LE)
Tidskr:  Lupus. 7 (suppl 1)
År:      1998-04
Side(r): 12-12
Konfer:  Fifth International Conference on SLE
Sted:    Cancun, Mexico
Språk:   eng
PublID:  r98028276
StatKat: f
LokalK:  s1

4
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bassøe, Carl-Fredrik
Medforf: Bruserud, Øystein
         UiB, Medisinsk avdeling B
Medforf: Pryme, I.F
Medforf: Vedeler, A
Tittel:  Ribosomal proteins sustain morphology, function and phenotype in
         acute myeloid leukemia blasts
Tidskr:  Leukemia Research
ISSN:    0145-2126
År:      1998
Volum:   22
Hefte:   4
Side(r): 329-339
SamEng:  Translation of mRNA is a prerequisite for cell proliferation,
         differentiation and viability. We have studied the effect of ribosome
         protein factors (GPRE) on acute myeloid leukemia (AML) blast cells.
         Ribosomes were isolated from MPC-11 cells using ultra-centrifugation.
         GPRE were extracted using a high KCl procedure. Blast cells from six
         AML patients were grownin suspension cultures for 24 and 96 h. GPRE
         or granulocyte macrophage-colony stimulating factor (GM-CSF) were
         added at the start of the incubation. GPRE, but not GM-CSF, prevented
         chromatin condensation and fragmentation of blast cell nuclei in
         AML-M2, -M4 and -M5 and the loss of nucleoli in AML-M2 and -M5. The
         fraction of phagocytosing blast cells in AML-M1, -M2, -M4 and -M5 was
         increased by GPRE. GPRE stimulated opsonin-dependent and -independent
         attachment and internalisation of N. meningitidis. GPRE increased the
         fraction of blasts expressing CD11b and CD32 in AML-M2 and -M5. GPRE
         diminished the fraction of AML-M5 cells bearing CD35 and CD32. GPRE
         also decreased the fraction of CD11c-bearing AML-M2 and -M5 cells.
         GM-CSF potentiated effects of GPRE in AML-M1, -M2, -M4 and -M5. GPRE
         and GM-CSF in combination affected phagocytosis and surface antigen
         expression in blast cells that were not influenced by either factor
         alone. Neither GPRE nor GM-CSF induced terminal differentiation or
         DNA-synthesis. We conclude that GPRE affects AML blast cell
         morphology, function and surface molecule expression, possibly by
         inhibiting apoptosis. The effects of GPRE may be mediated by
         ribosomal proteins that regulate translation and modulate the
         subcellular distribution of mRNA species.
Språk:   eng
PublID:  r98030306
StatKat: f
LokalK:  KAT 1

5
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Berentsen, Sigbjørn
Medforf: Bruserud, Øystein
         UiB, Medisinsk avdeling B
Medforf: Ulvestad, Elling
Tittel:  Storcellet granulær lymfocyttleukemi
Tidskr:  Tidsskrift for Den Norske Lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Hefte:   7
Side(r): 1045-1048
SamEng:  Large granular lymphocyte leukaemia (LGL leukaemia) is a rare,
         chronic lymphoproliferative bone marrow disease which can be
         considered a subtype of chronic T-cell lymphocytic leuka emia
         (T-CLL). We describe three patients with large granular lymphocyte
         leukaemia. They all suffered from chronic disease with neutropenia
         and relative lymphocytosis. An expansion ofmature lymphocytes with
         the CD3+, CD8+, CD57+ immunophenotype was demonstrated in all three
         patients. Two patients had a history of recurring infections.
         Serological findings compatible with rheumatic disease were present
         in all three patients, and two suffered from rheumatoid arthritis. We
         have made a brief survey of this disease, which is characterized by
         relative or absolute lymphocytosis,neutropenia, and an increased risk
         of infection. Rheumatoid arthritis and other associated autoimmune
         manifestations occur frequently. Large granular lymphocyte leukaemia
         should be considered a possible diagnosis in patients with chronic
         neutropenia and relative lymphocytosis, in particular if rheumatic
         manifestations are also present. Flow cytometric immunophenotyping is
         a sensitive method in diagnosing this disease.
Språk:   nor
PublID:  r98030220
StatKat: f
LokalK:  NKAT 8

6
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bruserud, Øystein
         UiB, Medisinsk avdeling B
Tittel:  Cellular immune responses in acute leukaemia patients with severe
         chemotherapy-induced leucopenia; characterization of the cytokine
         repertoire of clonogenic T cells
Tidskr:  Cancer Immunology and Immunotherapy
ISSN:    0340-7004
År:      1998
Volum:   46
Hefte:   4
Side(r): 221-228
SamEng:  T lymphocytes are important both for the host defence against
         infections and probably also as antileukaemic effector cells in
         patients with acute leukaemia. To investigate the T lymphocyte
         cytokine repertoire of clonogenic T lymphocytes, CD4+ and CD8+ T
         lymphocyte clones were prepared from acute leukaemia patients with
         chemotherapy-induced cytopenia (leucocytes <0.5x 10(9)/l). A majority
         of both CD4+ and CD8+ clones secreted detectable interleukin-2
         (IL-2), IL-10, IL-13,granulocyte/macrophage-colony-stimulating factor
         and interferon gamma (IFNgamma) in response to phytohaemagglutinin +
         accessory cells (Epstein-Barr-virus-transformed B cell line,
         80-Gy-irradiated). The CD4+ clones showed significantly higher levels
         of IL-10 secretion than the CD8+ clones. Decreased levels of IL-2,
         IL-13 and IFNgamma were observed when acute myelogenous leukaemia
         (AML) blasts were used instead of cells from the B cell line as
         accessory cells during phytohaemagglutinin activation, but the
         differences in IL-13 and IFNgamma levels were reversed by addition of
         exogenous IL-2. On the basis of these results we conclude: (i) the
         remaining clonogenic T lymphocytes derived from acute leukaemia
         patients with therapy-induced leucopenia can respond to activation
         with a broad cytokine response, and T-cell-derived cytokines may then
         contribute to cytokine responses during complicating infections in
         these patients; (ii) although T cells can modulate AML blast
         functions a nd mediate antileukaemic effects, the leukaemia blasts
         will also modulate T cell functions and alter the cytokine profile of
         activated T lymphocytes.
Språk:   eng
PublID:  r98030293
StatKat: f
LokalK:  KAT 1

7
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bruserud, Øystein
         UiB, Medisinsk avdeling B
Medforf: Foss, Brynjar
         UiB, Medisinsk avdeling B
Medforf: Ulvestad, Elling
Medforf: Hervig, T
Tittel:  Effect of acute myelogenous leukemia blasts on platelet release of
         soluble P-selectin and platelet-derived growth factor
Tidskr:  Platelets
ISSN:    0953-7104
År:      1998
Volum:   9
Side(r): 352-358
Språk:   eng
PublID:  r98030313
StatKat: f
LokalK:  KAT 1

8
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bruserud, Øystein
         UiB, Medisinsk avdeling B
Medforf: Berentsen, Sigbjørn
Medforf: Dahl, Inger-Marie S
Medforf: Grøttum, Kjell
Medforf: Sletnes, Kari
Tittel:  Fremtidig behov for spesialister i blodsykdommer
Tidskr:  Tidsskrift for Den norske lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Hefte:   16
Side(r): 2507-2510
SamEng:  Today there are not enough specialists in haematology in Norway.
         During the period 1990-1995 2.5 specialists in haematology qualified
         per year. In to meet future requirements for haematologists at
         Norwegian municipal and university hospitals, it has been estimated
         by the Norwegian Society for Haematology that the number of
         specialists qualif ying per year should be increased to ten for the
         next ten years.
Språk:   nor
PublID:  r98030279
StatKat: f
LokalK:  NKAT 8

9
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bruserud, Øystein
         UiB, Medisinsk avdeling B
Tittel:  IL-4, IL-10 and IL-13 in acute myelogenous leukemia
Tidskr:  Cytokines Cellular & Molecular Therapy
ISSN:    1368-4736
År:      1998
Volum:   4
Hefte:   3
Side(r): 187-198
SamEng:  Cytokines are important regulators of acute myelogenous leukemia
         (AML) blast proliferation. For a subset of patients the AML blasts
         show constituti cytokine secretion and can undergo autonomous
         proliferation in vitro, whereas for other patients the blasts are
         dependent on exogenous cytokines for proliferation. The capability of
         autocrine proliferation is an adverse prognostic factor in AML. The
         three cytokines interleukin (IL)-4, IL-10 and IL-13 modulate in vitro
         blast proliferation, but the final effect of each cytokine
         (enhancement/inhibition/no effect) depends on differences between
         individual patients as well as the presence of other exogenous
         cytokines. In contrast to these divergent effects on blast
         proliferation, all three cytokines inhibit constitutive in vitro
         cytokine secretion by AML blasts. Because of the divergent effects on
         blast proliferation, it seems less likely that clinical therapy with
         these cytokines can be used to directly modulate AML blast
         proliferation. However, their effects on normal immunocompetent cells
         (and possibly the antigen-presenting capacity of AML blasts) are
         easier to predict. Thus direct (therapy with exogenous IL-4, IL-10 or
         IL-13) or indirect (enhancement of endogenous release of IL-4, IL-10
         or IL-13) modulation of th ese cytokine effects on immunocompetent
         cells may become a useful clinical approach for enhancement of
         antileukemic immune effects. Such a modulation of immune reactivity
         can be used either as in vivo patient therapy or as manipulation of
         stem cell grafts prior to transplantation.
Språk:   eng
PublID:  r98029086
StatKat: f
LokalK:  KAT 1

10
PublKat: A07 (Leder, anmeldelse, kronikk i tidsskrift inkl. dagspresse (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bruserud, Øystein
         UiB, Medisinsk avdeling B
Medforf: Foss, Brynjar
         UiB, Medisinsk avdeling B
Tittel:  Serum thrombopoietin levels in acute leukemia patients with chemothera
         py-induced cytopenia--inverse correlation between serum levels and pla
         telet counts
Tidskr:  Leukemia
År:      1998
Volum:   12
Hefte:   10
Side(r): 1653-1654
Språk:   eng
PublID:  r98030308
StatKat: f
LokalK:  7

11
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bruserud, Øystein
         UiB, Medisinsk avdeling B
Medforf: Ulvestad, E.
Medforf: Berentsen, Sigbjørn
         UiB, Medisinsk avdeling B
Medforf: Bergheim, Jann
         UiB, Medisinsk avdeling B
Medforf: Nesthus, Ingerid
         UiB, Medisinsk avdeling B
Tittel:  T-lymphocyte functions in acute leukaemia patients with severe
         chemotherapy-induced cytopenia: Characterization of clonogenic T-cell
         proliferation
Tidskr:  Scandinavian Journal of Immunology
ISSN:    0300-9475
År:      1998
Volum:   47
Side(r): 54-62
SamEng:  Intensive chemotherapy for acute leukaemia is followed by a period of
         severe chemotherapy-induced leukopenia. We used a limiting dilution
         assay to investigate whether remaining CD4+ and CD8+ T lympocytes
         derived from such leukopenic patients could be activated and undergo
         clonogenic proliferation. The activation signal in our model was
         accessory cells (irradiated normal peripheral blood mononuclear
         cells) + phytohaemagglutinin (PHA)+ interleukin-2 (IL-2). During
         severe leukopenia a majority of circulating lymphocytes were CD4+ T
         cells. Clonogenic proliferating T lymphocytes were detected for all
         patients. Higher frequencies of clonogenic cells were dletected in
         the CD8+ subset as compared to the CD4+ subset. However,for both
         subsets frequencies of proliferating cells were decreased compared
         with healthy individuals. The CD4+ and CD8+ lymphocytes were also
         capable of proliferation in response to alloactivation, and accessory
         cells mainly containing acute myelogenous leukaemia blast were
         efficient as accessory cells for activation. For the CD4+ cells,
         increased proliferation was detected in the presence of acute
         myelogenous leukaemia (AML) blasts compared with normal accessory
         cells. Based on our results we conclude that: 1) although acute
         leukaemia patients with therapy-induced leukopenia have both a
         quantitative and a qualitative T-cell defect, 2) the remaining T-cell
         population includes a subset capable of clonogenic proliferation.
         Howe ver, 3) proliferation of the clonogenic CD4+ cells can be
         modulated by AML blasts.
Språk:   eng
PublID:  r98028168
StatKat: f
LokalK:  KAT 1

12
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Bruserud, Øystein
         UiB, Medisinsk avdeling B
Medforf: Ulvestad, Elling
Medforf: Berentsen, Sigbjørn
Medforf: Nesthus, Ingerid
         UiB, Medisinsk avdeling B
Tittel:  T-lymphocyte functions in acute leukaemia patients with severe
         chemotherapy-induced cytopenia: characterization of clonogenic T-cell
         proliferation.
Tidskr:  Scandinavian Journal of Immunology
ISSN:    0300-9475
År:      1998
Volum:   47
Hefte:   1
Side(r): 54-62
SamEng:  Intensive chemotherapy for acute leukaemia is followed by a period of
         severe chemotherapy-induced leukopenia. We used a limiting dilution
         assay to investigate whether remaining CD4+ and CD8+ T lymphocytes
         derived from such leukopenic patients could be activated and undergo
         clonogenic proliferation. The activation signal in our model was
         accessory cells (irradiated normal peripheral blood mononuclear
         cells) + phytohaemagglutinin (PHA) + interleukin-2 (IL-2). During
         severe leukopenia a majority of circulating lymphocytes were CD4+ T
         cells. Clonogenic proliferating T lymphocytes were detected for all
         patients. Higher frequencies of clonogenic cells were detected in the
         CD8+ subset as compared to the CD4+ subset. However, for both subsets
         frequencies of proliferating cells were decreased compared with
         healthy individuals. The CD4+ and CD8+ lymphocytes were also capable
         of proliferation in response to alloactivation, and accessory cells
         mainly containing acute myelogenous leukaemia blast were efficient as
         accessory cells for activation. For the CD4+ cells, increased
         proliferation was detected in the presence of acute myelogenous
         leukaemia (AML) blasts compared with normal accessory cells. Based on
         our results we conclude that: (1) although acute leukaemia patient s
         with therapy-induced leukopenia have both a quantitative and a
         qualitative T-cell defect, (2) the remaining T-cell population
         includes a subset capable of clonogenic proliferation. However, (3)
         proliferation of the clonogenic CD4+ cells can be modulated by AML
         blasts.
Språk:   eng
PublID:  r98030281
StatKat: f
LokalK:  KAT 1

13
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Cervera, R
Medforf: Font, J
Medforf: Sebastiani, G.D
Medforf: Khamashta, M. A.
Medforf: Hughes, G.R.V
Medforf: Ramos-Casals, M
Medforf: Gil, P
Medforf: Lavilla, P
Medforf: Aydintug, A.O
Medforf: Jedryka-Goral, A
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Tittel:  Morbidity and mortality in SLE during a 5-year period 1990-1995
Tidskr:  Lupus. 7 (suppl 1)
År:      1998-04
Side(r): 22-22
Konfer:  Fifth International Conference on SLE
Sted:    Cancun, Mexico
Språk:   eng
PublID:  r98028267
StatKat: f
LokalK:  s1

14
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Chelsom, Julia
         UiB, Medisinsk avdeling B
Medforf: Solberg, Claus Ola
         UiB, Medisinsk avdeling B
Tittel:  Vertebral osteomyelitis at a Norwegian university hospital 1987-97:
         clinical features, laboratory findings and outcome.
Tidskr:  Scandinavian Journal of Infectious Diseases
ISSN:    0036-5548
År:      1998
Volum:   30
Hefte:   2
Side(r): 147-151
SamEng:  Altogether 40 patients aged 13-91 y (average 58 y) with vertebral
         osteomyelitis were treated at the Bergen University Hospital between
         July 1987 and June 1997. All patients presented with back pain, 33
         (83) had vertebral tenderness, and 26 (65) patients were febrile.
         The duration of symptoms before diagnosis was < 3 weeks in 13
         patients, and from 3 to 16 weeks in the remaining 27 patients.
         C-reactive protein (CRP) level and erythrocyte sedimentation rate
         (ESR) were elevated in 39 and 38 patients, respectively.
         Staphylococcus aureus was the most frequent cause of osteomyelitis
         followed by Streptococcus spp., Escherichia coli and Mycobacterium
         tuberculosis. Magnetic resonance imaging was superior to other
         radiological methods and demonstrated changes consistent with
         osteomyelitis in all 23 patients examined with this method. 35
         patients survived. 18/35 surviving patients had pareses and 17
         underwent surgery with drainage of abscesses or laminectomy. All 35
         patients made a good recovery and only 3 patients experienced
         permanent pareses. The diagnosis of vertebral osteomyelitis is easily
         missed, and treatment is often delayed, particularly in the elderly
         in whom signs of sepsis may not manifest. However, persisting
         localized pain and tenderness over the spine together with elevated
         CRP and ESR should prompt the physician to consider vertebral
         osteomyelitis. Fever and leukocytosis may support the diagnosis, but
         may not always be present.
Språk:   eng
PublID:  r98028284
StatKat: f
LokalK:  KAT 1

15
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Ekwall, O
Medforf: Hedstrand, H.H.
Medforf: Grimelius, L
Medforf: Haavik, Jan
Medforf: Perheentupa, J
Medforf: Gustafsson, J
Medforf: Husebye, Eystein Sverre
         UiB, Medisinsk avdeling B
Medforf: Kämpe, O
Medforf: Rorsman, F
Tittel:  Identification of tryptophan hydroxylase as an intestinal autoantigen
Tidskr:  The Lancet
ISSN:    0140-6736
År:      1998
Volum:   352
Side(r): 279-283
Språk:   eng
PublID:  r98030333
StatKat: f
LokalK:  KAT 1

16
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Flö, Reinhardt W
         UiB, Medisinsk avdeling B
Medforf: Solberg, Claus Ola
         UiB, Medisinsk avdeling B
Tittel:  Pneumokokkvaksinen
Tidskr:  Tidsskrift for Den Norske Lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Side(r): 3799-3802
Språk:   nor
PublID:  r98030405
StatKat: f
LokalK:  NKAT 8

17
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Foss, Brynjar
         UiB, Medisinsk avdeling B
Medforf: Bruserud, Øystein
         UiB, Medisinsk avdeling B
Tittel:  Effect of platelet-derived growth factor on acute myelogenous leukemia
          blasts
Tidskr:  Bone Marrow Transplantation. 21
År:      1998-03
Side(r): 360-360
Konfer:  24th. Annual Meeting European Group for Blood and Marrow Transp
         lantation
Sted:    Italy
Språk:   eng
PublID:  r98030316
StatKat: f
LokalK:  s1

18
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Frostad, Stein
         UiB, Medisinsk avdeling B
Medforf: Bjerknes, Robert
         UiB, Pediatrisk institutt
Medforf: Abrahamsen, Jenny Foss
         UiB, Avdeling for patologi, Gades institutt
Medforf: Olweus, Johanna
Medforf: Bruserud, Øystein
         UiB, Medisinsk avdeling B
Tittel:  Insulin-like growth factor-1 (IGF-1) has a costimulatory effect on
         proliferation of committed progenitors derived from human umbilical
         cord CD34+ cells
Tidskr:  Stem Cells
ISSN:    1066-5099
År:      1998
Volum:   16
Hefte:   5
Side(r): 334-342
Emneord: umbilical cord hematopoietic stem cells, insulin-like growth factor
         -1 (IGF-1), granulocyte colony stimulating factor
SamEng:  ABSTRACT The effects of insulin-like growth factor -1 (IGF-1) on
         highly enriched human umbilical cord CD34+ cells was investigated in
         vitro. CD34+ were cultured in serumfree medium containing stem cell
         factor (SCF), granulocyte-macrophage colony stimulating factor
         (GM-CSF) and interleukin-3 (IL-3). Culture of CD34+ cells for one
         week in the presence of these cytokines resulted in a dose dependent
         increase in total cell number. Addition of granulocyte
         colony-stimulating factor (G-CSF) together with SCF+IL-3+GM-CSF
         increased the proliferation of myelopoietic cells as determined by
         number of cells expressing the myelomonocytic marker CD64 and the
         granulocytic marker CD15 without significantly altering the number of
         CD34+ c ells in the cultures. In the presence of G-CSF IGF-1 induced
         a dose-dependent increase in the total cell number, and a moderate,
         but significant increase in the percentages of CD15+,CD64+ cells with
         sustained CD34+ cell proliferation. We conclude that IGF-1 can
         enhance the in vitro proliferation of committed progenitor cells
         derived from umbilical cord CD34+ cell s.
Språk:   eng
PublID:  r98028394
StatKat: f
LokalK:  KAT 1

19
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Frostad, Stein
Medforf: Bjerknes, Robert
         UiB, Pediatrisk institutt
Medforf: Abrahamsen, Jenny Foss
Medforf: Olweus, J
Medforf: Bruserud, Øystein
         UiB, Medisinsk avdeling B
Tittel:  Insulin-like growth factor-1 (IGF-1) has a costimulatory effect on
         proliferation of committed progenitors derived from human umbilical
         cord CD34+ cells.
Tidskr:  Stem Cells
ISSN:    1066-5099
År:      1998
Volum:   16
Hefte:   5
Side(r): 334-342
SamEng:  The effects of insulin-like growth factor-1 (IGF-1) on highly
         enriched human umbilical cord CD34+ cells were investigated in vitro.
         CD34+ cells wer cultured in serum-free medium containing stem cell
         factor (SCF), GM-CSF, and interleukin-3 (IL-3). Culture of CD34+
         cells for one week in the presence of these cytokines resulted in a
         dose-dependent increase in total cell number. Addition of G-CSF
         together with SCF+IL-3+GM-CSF increased the proliferation of
         myelopoietic cells as determined by the number of cells expressing
         the myelomonocytic marker CD64 and the granulocytic marker CD15
         without significantly altering the number of CD34+ cells in the
         cultures. In the presence of G-CSF, IGF-1 induced a dose-dependent
         increase in the total cell number and a moderate but significant
         increase in the percentages of CD15+, CD64+ cells with sustained
         CD34+ cell proliferation. We conclude that IGF-1 can enhance th e in
         vitro proliferation of committed progenitor cells derived from
         umbilical cord CD34+ cells.
Språk:   eng
PublID:  r98030303
StatKat: f
LokalK:  KAT 1

20
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Gerdts, Eva
         UiB, Medisinsk avdeling A
Medforf: Svarstad, Einar
         UiB, Medisinsk avdeling A
Medforf: Aanderud, Sylvi
         UiB, Medisinsk avdeling B
Medforf: Myking, O.L.
Medforf: Lund-Johansen, Per
         UiB, Medisinsk avdeling A
Medforf: Omvik, Per
         UiB, Medisinsk avdeling A
Tittel:  Factors influencing reduction in blood pressure and left ventricular
         mass in hypertensive type-1 diabetic patients using Captopril or
         Doxazosin for months
Tidskr:  American Journal of Hypertension
ISSN:    0895-7061
År:      1998
Volum:   11
Side(r): 1178-1187
Språk:   eng
PublID:  r99000654
StatKat: f
LokalK:  KAT 1

21
PublKat: D03 (Foredrag/poster ved vit. konf. med publisert abstract (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Gorringe, A.R.
Medforf: Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Reddin, K.
Medforf: Johnson, A.S.
Medforf: Robinson, A.
Tittel:  Characterisation of human antibody responses to meningococcal transfer
         rin-binding proteins and evaluation of antigen-specific opsonophagocyt
         osis.
Tidskr:  Abstracts booklet, Society for General Microbiology, UK
År:      1998-03-30
Side(r): 30-30
Konfer:  Society for General Microbiology 140th Ordinary Meeting
Sted:    Nottingham, UK
Språk:   eng
PublID:  r99001693
LokalK:  s3

22
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Gustafsson, A
Medforf: Lund-Tønnesen, Stein
         UiB, Medisinsk avdeling B
Medforf: Berstad, Arnold
         UiB, Medisinsk avdeling A
Medforf: Midtvedt, T.
Medforf: Norin, E.
         UiB, Medisinsk avdeling B
Tittel:  Faecol short-term fatty acids in patients with antibiotic associated
         diarrhoea, before and after faecal enema treatment
Tidskr:  Scandinavian Journal of Gastroenterology
ISSN:    0036-5521
År:      1998
Side(r): 722-727
Språk:   eng
PublID:  r98030720
StatKat: f
LokalK:  KAT 1

23
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Skjærven, Rolv
         UiB, Medisinsk fødselsregister
Medforf: Brun, Johan G
         UiB, Medisinsk avdeling B
Medforf: Fagerhol, M.K
Tittel:  A longitudinal study of plasma calprotectin as a marker of disease
         activity in patients with SLE
Tidskr:  Scandinavian Journal of Rheumatology (suppl 108)
År:      1998
Side(r): 71-71
Konfer:  27th Scandinavian Congress of Rheumatology
Sted:    Aarhus, Denmark
Språk:   eng
PublID:  r98028268
StatKat: f
LokalK:  s1

24
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Hultén, B
Medforf: Bolstad, Anne Isine
Medforf: Ulvestad, E
Medforf: Jonsson, Roland
Tittel:  Reliability and sensitivity of diagnostic tests in Sjøgren's syndrome
Tidskr:  Arthritis and Rheumatism. 9 (suppl)
År:      1998-11
Side(r): S329-S329
Konfer:  American College of Rheumatoogy 62nd. National Meeting
Sted:    San Diego, USA
Språk:   eng
PublID:  r98029063
StatKat: f
LokalK:  a1

25
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Mollnes, T.E
Medforf: Rekvig, O.P
Tittel:  Seasonal variations in activity of systemic lupus erythematosus in a s
         unarctic region
Tidskr:  Clinical and Experimental Rheumatology. 16 (2)
År:      1998-03
Side(r): 160-160
Konfer:  18th Workshop for Rheumatology Research
Sted:    Athen
Språk:   eng
PublID:  r98028266
StatKat: f
LokalK:  s1

26
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Brun, Johan G
         UiB, Medisinsk avdeling B
Medforf: Mollnes, T.E
Medforf: Rekvig, O.P
Tittel:  Seasonal variations in activity of Systemic Lupus Erythematosus (SLE)
         in a subarctic region
Tidskr:  Scandinavian Journal of Rheumatology (suppl 108)
År:      1998
Side(r): 72-72
Konfer:  27th Scandinavian Congress of Rheumatology
Sted:    Aarhus, Denmark
Språk:   eng
PublID:  r98028270
StatKat: f
LokalK:  s1

27
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Hultén, B
Medforf: Bolstad, Anne Isine
Medforf: Ulvestad, E
Medforf: Jonsson, Roland
Tittel:  Sensitivity and reliability of diagnostic tests for primary Sjøgren's
         syndrome
Tidskr:  Scandinavian Journal of Rheumatology (suppl 108)
År:      1998
Side(r): 72-72
Konfer:  27th Scandinavian Congress of Rheumatology
Sted:    Aarhus, Denmark
Språk:   eng
PublID:  r98028269
StatKat: f
LokalK:  s1

28
PublKat: C11 (Rapport utgitt av institusjon, forening, o.a.)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Jonsson, Roland
         UiB, Avdeling for mikrobiologi og immunologi, Gades institutt
Tittel:  Sjögrens syndrom - en orientering for pasienter
Serie:   Tema
År:      1998
Hefte:   9
Side(r): 31 s.
Utgiver: Norsk revmatikerforbund
UtgSted: Oslo
Språk:   nor
PublID:  r98022457
StatKat: f
LokalK:  N KAT 3

29
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Jonsson, R
Tittel:  The influence of age on clinical features and laboratory parameters in
          primary Sjøgren's syndrome
Tidskr:  Clinical and Experimental Rheumatology. 16 (2)
År:      1998-03
Side(r): 156-156
Konfer:  18th Workshop for Rheumatology Research
Sted:    Athen
Språk:   eng
PublID:  r98028265
StatKat: f
LokalK:  s1

30
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Tittel:  The influence of age on clinical features and laboratory parameters in
          primary Sjøgren's syndrome
Tidskr:  Scandinavian Journal of Rheumatology (suppl 108)
År:      1998
Side(r): 110-110
Konfer:  27th Scandinavian Congress of Rheumatology
Sted:    Aarhus, Denmark
Språk:   eng
PublID:  r98028272
StatKat: f
LokalK:  s1

31
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Halse, A.-K.
Medforf: Tengner, P
Medforf: Wahren-Herlenius, M
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Jonsson, R
Tittel:  Frequency of IFN-y, IL-6 and IL-10 secreting cells in peripheral
         blood from primary Sjøgren's syndrome
Tidskr:  Clinical and Experimental Rheumatology. 16 (2)
År:      1998-03
Side(r): 67-67
Konfer:  18th European Workshop for Rheumatology Research
Sted:    Athen
Språk:   eng
PublID:  r98028263
StatKat: f
LokalK:  s

32
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Halse, A.-K.
Medforf: Tengner, P
Medforf: Wahren-Herlenius, M
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Jonsson, R
Tittel:  Increased frequency of IL-6 and IL-10 secreting cells in peripheral
         blood from primary Sjøgren's syndrome patients
Tidskr:  Scandinavian Journal of Immunology. 47 (6)
År:      1998
Konfer:  Scandinavian Society Immunology 29th. Meeting
Sted:    Copenhagen, Denmark
Språk:   eng
PublID:  r98029046
StatKat: f
LokalK:  a

33
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Harthug, Stig
         UiB, Medisinsk avdeling B
Medforf: Langeland, Nina
         UiB, Medisinsk avdeling B
Medforf: Digranes, Asbjørn
Medforf: Simonsen, G.S.
Medforf: Olsvik, Ø.
Medforf: Sundsfjord, A.
Tittel:  Infeksjoner forårsaket av multiresistente enterokokker i Norge
Tidskr:  Tidsskrift for Den norske lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Hefte:   26
Side(r): 4070-4073
Språk:   nor
PublID:  r99000713
StatKat: f
LokalK:  NKAT 8

34
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Harthug, Stig
         UiB, Medisinsk avdeling B
Medforf: Langeland, Nina
         UiB, Medisinsk avdeling B
Tittel:  Outbreak of multiresistant enterococcus faecium in a Norwegian univers
         ity hospital - riskfactors for infection
Tidskr:  J Hospital Infection . 40 (Suppl A)
År:      1998
Side(r): P3.2.18
Konfer:  J Hospital Infection Society
Sted:    Edinburgh
Språk:   eng
PublID:  r99000714
LokalK:  s1

35
PublKat: A07 (Leder, anmeldelse, kronikk i tidsskrift inkl. dagspresse (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Harthug, Stig
         UiB, Medisinsk avdeling B
Medforf: Vindenes, H.A.
Medforf: Onarheim, H.
Medforf: Digranes, Asbjørn
Tittel:  Utbrudd med multiresistente Acinetobacter baumanii ved
         Brannskadeavsnittet, Haukeland sykehus
Tidskr:  MSIS-ukerapport
År:      1998
Hefte:   20
Språk:   nor
PublID:  r99000717
LokalK:  N7

36
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Holmboe, J
Medforf: Giercksky, K-E
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Mellbye, O.J
Medforf: Matheson, I
Medforf: Hagerup-Jensen, I
Tittel:  Silikonproteser nok en gang - hva er status?
Tidskr:  Tidsskrift for Den Norske Lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Side(r): 261-262
Språk:   nor
PublID:  r98028257
StatKat: f
LokalK:  NKAT 8

37
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Holmås, G.
Medforf: Gilhus, Nils Erik
         UiB, Institutt for nevrologi
Medforf: Gjerde, Ivar Otto
Medforf: Lund-Tønnesen, Stein
         UiB, Medisinsk avdeling B
Medforf: Langørgen, J.
Tittel:  Sårbotulisme ved heroinmisbruk
Tidskr:  Tidsskrift for Den norske lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Side(r): 4357-4359
Språk:   nor
PublID:  r98030717
StatKat: f
LokalK:  NKAT 8

38
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Husebye, Eystein S.
         UiB, Medisinsk avdeling B
Medforf: Aanderud, Sylvi
         UiB, Medisinsk avdeling B
Tittel:  Primær binyrebarksvikt - en diagnostisk utfordring
Tidskr:  Tidsskrift for Den norske lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Side(r): 542-544
Språk:   nor
PublID:  r98030385
StatKat: f
LokalK:  NKAT 8

39
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Jarvis, L.M.
Medforf: Bell, H
Medforf: Simmonds, P.
Medforf: Hawkins, A.
Medforf: Hellum, K
Medforf: Harthug, Stig
         UiB, Medisinsk avdeling B
Tittel:  The effect of treatment with alpha-interferon on hepatitis G/GBV-C
         viraemia. The Construct Group.
Tidskr:  Scandinavian Journal of Gastroenterology
ISSN:    0036-5521
År:      1998
Volum:   33
Side(r): 195-200
Språk:   eng
PublID:  r99000715
StatKat: f
LokalK:  KAT 1

40
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Jonsson, Roland
Medforf: Brandtzaeg, P.
Medforf: Nerland, AH
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Tittel:  Immunopathology of mucous membranes and exocrine glands
Tidskr:  Arthritis and Rheumatism
ISSN:    0004-3591
År:      1998
Volum:   41
Side(r): 572-576
Språk:   eng
PublID:  r98028254
StatKat: f
LokalK:  KAT 1

41
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Kemp, E
Medforf: Ajjan, R.A
Medforf: Husebye, Eystein Sverre
         UiB, Medisinsk avdeling B
Medforf: Peterson, P
Medforf: Uibo, R
Medforf: Imrie, H
Medforf: Pearce, S
Medforf: Watson, P.F
Medforf: Weetman, A.P
Tittel:  A cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism is
         associated with autoimmune Addison's disease in English patients
Tidskr:  Clinical Endocrinology
ISSN:    0300-0664
År:      1998
Volum:   49
Side(r): 609-614
Språk:   eng
PublID:  r98030339
StatKat: f
LokalK:  KAT 1

42
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Halstensen, Alfred
         UiB, Medisinsk avdeling B
Medforf: Bassøe, Carl-Fredrik
         UiB, Medisinsk avdeling B
Tittel:  Flow cytometric quantitation of human opsonin-dependent phagocytosis
         and oxidative burst responses to meningococcal antigens
Tidskr:  Cytometry
ISSN:    0196-4763
År:      1998
Volum:   33
Hefte:   4
Side(r): 406-413
SamEng:  A one-step flow cytometric (FCM) assay has been developed to
         quantifyboth opsonin- and antigen-dependent phagocytosis and
         intraphagocyte oxidative burst responses. Meningococcal outer
         membrane structures (OMV) were adsorbed to fluorescent polystyrene
         beads, opsonized with serum, and exposed to leukocytes. FCM
         parameters of phagocytosis wereevaluated in combinations with
         oxidative burst indicators. Rhodamine-123 was the most sensitive
         indicator and was compatible with quantitation of phagocytosis. The
         phagocytosis and oxidative burst responses induced by OMV beads were
         dependent on both antigens and opsonins. Increased human opsonic
         responses against OMV were induced during clinical meningococcal d
         isease. A dissociation was noted between phagocytosis and oxidative
         burst in individual cells, indicating that functional opsonins
         against OMV components may differin their ability to stimulate
         phagocytosis and oxidative burst responses. The method facilitates
         evaluation of purified bacterial structures as mediators of
         opsonin-dependent phagocytosis an d intracellular oxidative microb
         icidal mechanisms, which is of interest in the complex process of
         selecting bacterial antigens as constituents of certain vaccines.
Språk:   eng
PublID:  r99000865
StatKat: f
LokalK:  KAT 1

43
PublKat: D03 (Foredrag/poster ved vit. konf. med publisert abstract (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Guttormsen, Hilde-Kari
Medforf: Wetzler, L.M.
Medforf: Aaberge, I.S.
Medforf: Holst, J.
Medforf: Gorringe, A.R.
Medforf: Reddin, K.
Medforf: Smith, Ingrid
         UiB, Medisinsk avdeling B
Medforf: Sørnes, Steinar
         UiB, Medisinsk avdeling B
Medforf: Halstensen, Alfred
         UiB, Medisinsk avdeling B
Tittel:  Patient opsonins against specific meningococcal outer membrane compone
         nts.
År:      1998-11-01
Konfer:  Eleventh International Pathogenic Neisseria Conference
Sted:    Nice, France
Språk:   eng
PublID:  r99001694
StatKat: f
LokalK:  s3

44
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Lund-Tønnesen, Stein
         UiB, Medisinsk avdeling B
Medforf: Berstad, Arnold
         UiB, Medisinsk avdeling A
Medforf: Schreiner, Aksel
         UiB, Medisinsk avdeling B
Medforf: Midtvedt, T.
Tittel:  Clostridiuim difficile-assosiert diaré behandlet med homolog feces
Tidskr:  Tidsskrift for Den norske lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Side(r): 1027-1030
Språk:   nor
PublID:  r98030722
StatKat: f
LokalK:  NKAT 8

45
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Lønning, Per Eystein
         UiB, Seksjon for onkologi
Tittel:  Pharmacological profiles of exemestane and formestane steroidal
         aromatase inhibitors used for treatment of postmenopausal breast
         cancer
Tidskr:  Breast Cancer Research and Treatment
ISSN:    0167-6806
År:      1998
Volum:   49
Side(r): 45-52
Språk:   eng
PublID:  r98030669
StatKat: f
LokalK:  KAT 1

46
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Mohn, S.C.
Medforf: Harthug, Stig
         UiB, Medisinsk avdeling B
Medforf: Langeland, Nina
         UiB, Medisinsk avdeling B
Tittel:  Outbreak of multiresistant enterococcus faecium in a Norwegian univers
         ity hospital - riskfactors for faecal colonization
Tidskr:  J Hospital Infection. 40 (Suppl A)
År:      1998
Side(r): P3.2.21
Konfer:  J Hospital Infection Society
Sted:    Edinburgh
Språk:   eng
PublID:  r99000716
LokalK:  s1

47
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Myhre, A-G
Medforf: Bjørses, P
Medforf: Dalen, A
Medforf: Husebye, Eystein Sverre
         UiB, Medisinsk avdeling B
Tittel:  Three sisters with Addison's disease
Tidskr:  The Journal of Clinical Endocrinology and Metabolism
ISSN:    0021-972X
År:      1998
Volum:   83
Side(r): 4204-4206
Språk:   eng
PublID:  r98029082
StatKat: f
LokalK:  KAT 1

48
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Nedrebø, B.G.
Medforf: Ericsson, U.-B.
         Malmö universitetssjukhus
Medforf: Nygård, Ottar
         UiB, Seksjon for medisinsk statistikk
Medforf: Refsum, Helga
         UiB, Institutt for farmakologi
Medforf: Ueland, Per Magne
         UiB, Institutt for farmakologi
Medforf: Aakvaag, Asbjørn
         UiB, Institutt for klinisk biokjemi
Medforf: Aanderud, Sylvi
         UiB, Medisinsk avdeling B
Medforf: Lien, Ernst Asbjørn
         UiB, Institutt for farmakologi
Tittel:  Plasma total homocysteine levels in hyperthyroid and hypothyroid patie
         nts
Tidskr:  Metabolism
ISSN:    0026-0495
År:      1998
Volum:   47
Hefte:   1
Side(r): 89-93
SamEng:  We found a higher plasma concentration of total homocysteine (tHcy),
         an independent risk factor for cardiovascular disease, in patients wi
         th hypothyroidism (mean, 16.3 mol/L; 95% confidence interval [Cl],
         14.7 to 17.9 mol/L) than in healthy controls (mean, 10.5 mol/L: 9
         5% CI, 10.1 to 10.9 mu mol/L). The tHcy level of hyperthyroid pa tien
         ts did not differ significantly from that of the controls. Serum crea
         tinine was higher in hypothyroid patients and lower in hyperthyroid p
         atients than in controls, whereas serum folate was higher in hyperthy
         roid patients compared with the two other groups. In multivariate ana
         lysis, these differences did not explain the higher tHcy concentratio
         n in hypothyroidism. We confirmed the observation of elevated serum c
         holesterol in hypothyroidism, which together with the hyperhomocystei
         nemia may contribute to an accelerated atherogenesis in these patient
         s.
Språk:   eng
PublID:  r98024551
StatKat: f
LokalK:  KAT 1

49
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Omholt, K
Medforf: Halse, A.-K.
Medforf: Nerland, AH
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Jonsson, R
Tittel:  Distribution of HLA class II alleles in a Norwegian population of
         Sjøgren's syndrome patients
Tidskr:  Scandinavian Journal of Immunology. 47 (6)
År:      1998
Konfer:  Scandinavian Society Immunology 29th. Meeting
Sted:    Copenhagen, Denmark
Språk:   eng
PublID:  r98029050
StatKat: f
LokalK:  a

50
PublKat: D03 (Foredrag/poster ved vit. konf. med publisert abstract (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Plested, J.S.
Medforf: Ferry, B.F.
Medforf: Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Makepeace, K.
Medforf: Griffiths, H.G.
Medforf: Bird, A.G.
Medforf: Moxon, E.R.
Tittel:  A flow cytometric based opsonophagocytosis assay to study the role of
         complement and antigen-specific antibody in the uptake of Neisseria
         meningiti by human peripheral blood monocytes and granulocytes.
Tidskr:  Immunology 95(suppl 1)
År:      1998-12-01
Side(r): 89-89
Konfer:  6th Annual Congress of British Society of Immunology
Sted:    Harrogate
Språk:   eng
PublID:  r99001690
StatKat: f
LokalK:  s

51
PublKat: D03 (Foredrag/poster ved vit. konf. med publisert abstract (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Plested, J. S.
Medforf: Ferry, B.F.
Medforf: Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Makepeace, K.
Medforf: Griffiths, H.G.
Medforf: Bird, A.G.
Medforf: Moxon, E.R.
Tittel:  Functional studies of antibodies to inner core lipopolysaccharide
         (LPS) of Neisseria meningitidis (Nm) group B, using a flow
         cytometric-based opsonophagocytosis assay.
År:      1998-11-01
Konfer:  Eleventh International Pathogenic Neisseria Conference
Sted:    Nice, France
Språk:   eng
PublID:  r99001689
StatKat: f
LokalK:  s

52
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Rosenqvist, E.
         Nasjonalt institutt for folkehelse, Oslo
Medforf: Høiby, E. A.
Medforf: Bjune, Gunnar
Medforf: Aase, A.
Medforf: Halstensen, Alfred
         UiB, Medisinsk avdeling B
Medforf: Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Holst, J.
Medforf: Michaelsen, T.E.
Medforf: Nøkleby, H.
Medforf: Frøholm, L.O.
Medforf: Closs, O.
Tittel:  Effect of aluminium hydroxide adjuvant and serogroup C polysaccharide
         on the immunogenicity and reactogenicity of a group B Neisseria mening
         itidis outer membrane vesicle vaccine
Tidskr:  Developments in Biological Standardization
ISSN:    0301-5149
År:      1998
Volum:   92
Side(r): 323-333
SamEng:  Three different formulations of an outer membrane vesicle (OMV) vacci
         ne against group B meningococcal disease have been prepared and teste
         d for immunogenicity and reactogenicity in adult volunteers. The vacc
         ines were prepared with or without aluminium hydroxide and serogroup
         C-polysaccharide (C-ps). Doses from 12.5 to 100 mu g protein were giv
         en twice at a sixweeks' interval. All three formulations were well to
         lerated and highly immunogenic, inducing bactericidal and opsonizing
         antibodies in humans. Adsorption of OMVs to aluminium hydroxide reduc
         ed the pyrogenicity in rabbits. The differences in immunogenicity bet
         ween the formulations were relatively small, but after the second dos
         ea stronger booster response was obser ved when the vaccines were ads
         orbed. Thus, a formulation with OMVs and C-ps represents a safe and h
         ighly immunogenic vaccine, even without alumini um hydroxide.
Språk:   eng
PublID:  r97001573
StatKat: f
LokalK:  KAT 1

53
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Rosenqvist, E.
Medforf: Høiby, E. A.
Medforf: Bjune, Gunnar
Medforf: Aase, A.
Medforf: Halstensen, Alfred
         UiB, Medisinsk avdeling B
Medforf: Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Paulssen, J.
Medforf: Holst, J.
Medforf: Michaelsen, T.E.
Medforf: Nøkleby, H.
Medforf: Frøholm, L.O.
Medforf: Closs, O.
Tittel:  Effect of aluminium hydroxide and meningococcal serogroup C capsular
         polysaccharide on the immunogenicity and reactogenicity of a group B
         Neisseria meningitidis outer membrane vesicle vaccine.
Tidskr:  Developments in Biological Standardization
ISSN:    0301-5149
År:      1998
Volum:   92
Side(r): 323-333
SamEng:  Three different formulations of an outer membrane vesicle (OMV)
         vaccine against group B meningococcal disease have been prepared and
         tested for immunogenicity and reactogenicity in adult volunteers.
         Thevaccines were prepared with or without aluminium hydroxide and
         serogroup C-polysaccharide (C-ps). Doses from 12.5 to 100 micrograms
         protein were given twice ata six weeks' interval. All three
         formulations were well tolerated and highly immunogenic, inducing
         bactericidal and opsonizing antibodies in humans. Adsorption of OMVs
         to aluminium hydroxide reduced the pyrogenicity in rabbits. The
         differences in immunogenicity between the formulations were
         relatively small, but after the seconddose a stronger booster
         response wa s observed when the vaccines were adsorbed. Thus, a
         formulation with OMVs and C-ps represents a safe and highly
         immunogenic vac cine, even without aluminium hydroxide.
Språk:   eng
PublID:  r99000385
StatKat: f
LokalK:  KAT 1

54
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Skjöldberg, F
Medforf: Grimelius, L
Medforf: Rorsman, F
Medforf: Van Schothorst, E.W
Medforf: Winqvist, O
Medforf: Karlsson, F.A
Medforf: Åkerström, G
Medforf: Kämpe, O
Medforf: Husebye, Eystein Sverre
         UiB, Medisinsk avdeling B
Tittel:  A family with hereditary extra-adrenal paragangliomas without
         evidence for mutations in the Von Hippel Lindau disease or ret genes
Tidskr:  Clinical Endocrinology
ISSN:    0300-0664
År:      1998
Volum:   48
Side(r): 11-16
Språk:   eng
PublID:  r98030328
StatKat: f
LokalK:  KAT 1

55
PublKat: D03 (Foredrag/poster ved vit. konf. med publisert abstract (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Smith, Ingrid
         UiB, Medisinsk avdeling B
Medforf: Lehmann, Anne Kristine
         UiB, Medisinsk avdeling B
Medforf: Lie, L.
Medforf: Digranes, A.
Medforf: Caugant, Dominique A
Medforf: Høiby, E.A.
Medforf: Frøholm, L.O.
Medforf: Halstensen, Alfred
         UiB, Medisinsk avdeling B
Tittel:  Meningococcal disease outbreak due to a new strain C:15:P1.7,16 in
         Western Norway, and selective carriage eradication of this strain.
År:      1998-11
Konfer:  Eleventh International Pathogenic Neisseria Conference
Sted:    Nice, France
Språk:   eng
PublID:  r99001688
StatKat: f
LokalK:  s

56
PublKat: A05 (Kapittel i faglig bok, rapport m.v. (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Solberg, Claus Ola
         UiB, Medisinsk avdeling B
Tittel:  Akutt bakteriell meningitt
Tidskr:  Norsk legemiddelhåndbok 1998-99 for helsepersonell
Red:     Vennerød, A.M
ISBN:    82-90732-06-6
År:      1998
Side(r): 118-123
Utgiver: Oslo: Norsk legemiddelhåndbok I/S
Språk:   nor
PublID:  r98030396
StatKat: f
LokalK:  N6

57
PublKat: A05 (Kapittel i faglig bok, rapport m.v. (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Solberg, Claus Ola
         UiB, Medisinsk avdeling B
Tittel:  Osteomyelitt
Tidskr:  Norsk legemiddelhåndbok 1998-99 for helsepersonell
Red:     Vennerød, A.M
ISBN:    82-90732-06-6
År:      1998
Side(r): 126-128
Utgiver: Oslo: Norsk legemiddelhåndbok I/S
Språk:   nor
PublID:  r98030400
StatKat: f
LokalK:  N6

58
PublKat: A05 (Kapittel i faglig bok, rapport m.v. (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Solberg, Claus Ola
         UiB, Medisinsk avdeling B
Tittel:  Sepsis
Tidskr:  Norsk legemiddelhåndbok 1998-99 for helsepersonell
Red:     Vennerød, A.M
ISBN:    82-90732-06-6
År:      1998
Side(r): 113-118
Utgiver: Oslo: Norsk legemiddelhåndbok I/S
Språk:   nor
PublID:  r98030393
StatKat: f
LokalK:  N6

59
PublKat: A17 (Artikkel i populærvitenskapelig tidsskrift)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Solberg, Claus Ola
         UiB, Medisinsk avdeling B
Tittel:  Stopp utarmingen av sykehusene i Hordaland
Tidskr:  Bergens Tidende
År:      1998-11-18
Språk:   nor
PublID:  r98030386
StatKat: f
LokalK:  N5

60
PublKat: A04 (Artikkel i norsk vitenskapelig tidsskrift (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Storstein, Anette
         UiB, Institutt for nevrologi
Medforf: Gjerde, Ivar Otto
         UiB, Institutt for nevrologi
Medforf: Vedeler, Christian
         UiB, Institutt for nevrologi
Medforf: Nesthus, Ingerid
         UiB, Medisinsk avdeling B
Tittel:  POEMS-syndromet - en sjelden multiorgansykdom
Tidskr:  Tidsskrift for Den norske lægeforening
ISSN:    0029-2001
År:      1998
Volum:   118
Hefte:   21
Side(r): 3274-3277
SamNor:  POEMS-syndromet er en sjelden multiorgansykdom hvor hovedsymptomene
         er polyneuropati, organmegali, endokrinopati, monoklonal gammopati og
         hudforandringer. Gammopatien er ofte betinget i et myelom eller et
         plasmocytom som kan påvises radiologisk og histologisk. Patogenesen
         er uklar, men sannsynligvis immunbetinget. Utviklingen av syndromet
         kan skje over flere år. Primært må den hematologiske grunnsykdom
         behandles. I en del tilfeller kan dette stabilisere utviklingen av
         tilstanden. Det er viktig å kjenne til tilstanden for å kunne se
         sammenhe ngen mellom de ulike symptomene og sikre at riktig
         behandling blir igangsatt. Vi presenterer tre pasienter med
         POEMS-syndromet og en gjennomgang av litteraturen.
SamEng:  POEMS syndrome is a rare multisystemic disorder characterized by a
         variable constellation of polyneuropathy, organomegaly,
         endocrinopathy, monoclonal gammopathy and skin changes. The syndrome
         is believed to be immune-mediated and is probably related to the
         pathological monoclonal component caused by a myeloma or a
         plasmocytoma. The treatment is aimed at the und erlying plasma cell
         dyscrasia. We have studied three patients with this rare syndrome.
         This article presents the clinical picture of each one and a survey
         of the literature.
Språk:   nor
PublID:  r98028158
StatKat: f
LokalK:  NKAT 8

61
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Tengnér, P.
         Karolinska Institutet, Stockholm, Sweden
Medforf: Halse, Anne-Kristine
         UiB, Avdeling for mikrobiologi og immunologi, Gades institutt
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Jonsson, Roland
         UiB, Avdeling for mikrobiologi og immunologi, Gades institutt
Medforf: Wahren-Herlenius, M.
Tittel:  Detection of anti-Ro/SSA and anti-La/SSB autoantibody producing cells
         in salivary glands from patients with Sjögren´s syndrome
Tidskr:  Arthritis Rheum
År:      1998
Volum:   41
Hefte:   12
Side(r): 2238-2248
Språk:   eng
PublID:  r99012149
StatKat: a
LokalK:  KAT 1

62
PublKat: D02 (Foredrag/poster ved vit. konf. med publisert artikkel (t.o.m. 1998))
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Tengner, P
Medforf: Halse, A.-K.
Medforf: Wahren-Herlenius, M
Medforf: Haga, Hans-Jacob
         UiB, Medisinsk avdeling B
Medforf: Jonsson, R
Tittel:  Increased number of IL-6 and IL-10 secreting cells in peripheral
         blood from patients with primary Sjøgren's syndrome
Tidskr:  Arthritis and Rheumatism. 9 (suppl)
År:      1998-11
Side(r): S298-S298
Konfer:  American College of Rheumatology
Sted:    San Diego
Språk:   eng
PublID:  r98029077
StatKat: f
LokalK:  a

63
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Undeland, K.A.
         UiB, Medisinsk avdeling A
Medforf: Hausken, Trygve
         UiB, Medisinsk avdeling A
Medforf: Gilja, Odd Helge
         UiB, Medisinsk avdeling A
Medforf: Aanderud, Sylvi
         UiB, Medisinsk avdeling B
Medforf: Berstad, Arnold
         UiB, Medisinsk avdeling A
Tittel:  Gastric meal accommodation and symptoms in diabetes. A
         placebocontrolled study of glyceryl trinitrate.
Tidskr:  European Journal of Gastroenterology & Hepatology
ISSN:    0954-691x
År:      1998
Volum:   10
Hefte:   8
Side(r): 677-681
SamEng:  OBJECTIVE: To study mechanisms behind postprandial symptoms in
         patients with diabetes mellitus and the effect of nitric oxide (NO)
         on gastric accommodation and symptoms in these patients. DESIGN: A
         double-blind, placebo-controlled, randomized trial was designed in
         20patients with type 1 diabetes (10 male and 10 female, aged 35.3 +/-
         7.6 years). METHODS: 0.5 mg sublingual glyceryl trinitrate (GTN), a
         donor of exogenous NO, or placebo was administered 5 min prior to a
         500 ml soup meal. Gastric accommodation of the meal was assessed by
         abdominal ultrasound. Accommodation in proximal stomach was
         visualized in a sagittal area (Psa) and a frontal diameter (Pfd) and
         accommodation in distal stomach was visualized in a sagittal area of
         the antrum (Asa). Symptoms were assessed using visual analogue
         scales. RESULTS: Psa correlated significantly (r = 0.57, P = 0.015)
         with perception of fullness 5 min after the meal, whereas Pfd
         correlated significantly (r = 0.67, P = 0.004) with nausea at 15 and
         at 25 min after the meal. Asa correlated (r = 0.50, P = 0.05 ) with
         pain at 5 min, 10 min (r = 0 .50, P = 0.05) and 25 min (r = 0.68, P
         =0.007). GTN had no significant effect on Psa or Pfd, but reduced
         significantly (P = 0.05) Asa (1 3.5+/- 4.5 cm2 with GTN vs 16.1 +/-
         4.3 cm2with placebo). GTN increased significantly (P = 0.04) the
         intragastric proximal/distal meal distribution ratio
         (proximal/distalsagittal area), but had no significant effect on
         symptom scores. CONCLUSION: In patients with diabetes, a large
         proximal stomach is associated with perception of fullness and a
         large antrum is associated with perception of pain after a me al.
         Sublingual administration of GTN prior to the meal decreases the
         antral area andimproves the intragastric meal distribution, but fails
         to improve symptoms.
Språk:   eng
PublID:  r99000672
StatKat: f
LokalK:  KAT 1

64
PublKat: A11 (Artikkel i internasjonalt vitenskapelig tidsskrift med referee)
Instit:  Universitetet i Bergen, Det medisinske fakultet, Medisinsk avdeling B
Forf:    Undeland, K.A.
         UiB, Medisinsk avdeling A
Medforf: Hausken, Trygve
         UiB, Medisinsk avdeling A
Medforf: Gilja, Odd Helge
         UiB, Medisinsk avdeling A
Medforf: Aanderud, Sylvi
         UiB, Medisinsk avdeling B
Medforf: Berstad, Arnold
         UiB, Medisinsk avdeling A
Tittel:  Gastric meal accommodation studied by ultrasound in diabetes.
         Relation to vagal tone.
Tidskr:  Scandinavian Journal of Gastroenterology
ISSN:    0036-5521
År:      1998
Volum:   33
Hefte:   3
Side(r): 236-241
Språk:   eng
PublID:  r99000712
StatKat: f
LokalK:  KAT 1


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